Top Videos

  1. Macrophage uptake of HIV-1-infected T cells

    Jurkat T cells were infected for 7–10 days with HIV-1 expressing GFP, mixed with adherent monocyte-derived macrophages, and immediately imaged. Time-lapse imaging occurred over approximately 2 hr.

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  2. Dolphins Learn Foraging Skill “Shelling” from Peers

    Dolphins in Shark Bay, Western Australia, use empty giant gastropod shells to trap prey. Wild et al. integrate genetic, behavioral, and environmental data in a network-based diffusion analysis to show that “shelling” spreads socially among associates. This study provides the first quantitative evidence for non-vertical cultural transmission of foraging behavior in toothed whales.

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  3. Human and dog brains both have dedicated "voice areas"

    The video presents the first study to compare brain function between humans and any nonprimate animal. Scientists at MTA-ELTE Comparative Ethology Research Group in Hungary found that dogs and humans use similar neural mechanisms to process social information in voices. The fact that dogs can be trained to lie motionless during fMRI tests opens up the space for a new branch of comparative neuroscience.

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  4. Origin of Follicular Dendritic Cells

    Adriano Aguzzi uses cookies baked by his daughter to explain how follicular dendritic cells can differentiate from a surprisingly ubiquitous population of precursors in inflammatory conditions.

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  5. PINK1/Parkin derails damaged mitochondria

    Thomas Schwarz shows how Parkinson's disease proteins quarantine damaged mitochondria by disconnecting them from the microtubule network.

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  6. How does CaMKII sense specific calcium waves?

    John Kuriyan and his team reveal a flower-like unfurling mechanism that allows different isoforms of CaMKII to sense particular frequencies of calcium spikes.

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  7. Nucleosome Clutches

    Using STORM microscopy, Cosma and colleagues find that nucleosomes associate in discrete clutches along the chromatin fiber and clutch size correlates with cell identity.

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  8. How Legs Were Lost during Snake Evolution

    Most snakes are completely limbless, but some snakes diverged from the lineage leading to the advanced snakes before legs were completely eliminated. Pythons are a group of snakes that retain a pelvis and a small remnant of the femur, known as the spur. Francisca Leal and Marty Cohn at the University of Florida discovered that deletions in an enhancer of the Sonic hedgehog gene are responsible for the arrest of limb development in python embryos. Unexpectedly, python embryos form pre-cartilaginous models of the entire leg skeleton, down to the foot, but these embryonic leg structures degenerate before hatching, leaving only the spurs.

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  9. Single-Cell Live Imaging of Early Embryo Development

    Nicolas Plachta and his colleagues at the A*Star Institute in Singapore developed a way to measure the dynamics of transcription factor-DNA binding interaction in single cells of live mouse embryos with surprising results of how the duration of the interaction affects cell fate in early development.

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  10. Biology behind seed dispersal by explosion

    Some plants disperse their seeds by exploding seed pods. Angela Hay and her colleagues explain how it happens.

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